Western Australia study finds bee venom can quickly kill breast cancer cells
A new Australian study found that the venom of bees can quickly kill breast cancer cells. The main component of the venom, when combined with current chemotherapy drugs, can extremely effectively reduce the growth of tumors in mice.
The results of this study by the Harry Perkins Institute of Medical Research in Perth, Western Australia have been published in the journal Nature Precision Oncology. Researchers have discovered that a component of bee venom called "melissarin" can kill cancer cells. Researchers have synthesized melittin and found that it has the same anti-cancer effect as most bee venoms.
Dr. Ciara Duffy, who led the research, hopes that this discovery will promote the development of triple-negative breast cancer treatments.
Triple-negative breast cancer accounts for 10% to 15% of all breast cancers, and there is currently no effective targeted therapy.
Dr. Duffy told the Australian Broadcasting Corporation: "We have found that the venom of bees is very effective in killing some very aggressive breast cancer cells, and its concentration will not cause harm to normal cells."
The study found that a certain concentration of bee venom killed 60% of triple-negative breast cancer cells and HER100-rich breast cancer cells within 2 minutes, while the effect on normal cells was minimal.
"We also found that it interfered with the main information transmission or cancer signaling pathways, and these are the basis for the growth and replication of cancer cells." Dr. Duffy said.
The chief scientist of Western Australia, Professor Peter Klinken, said that this is an incredible and exciting discovery that provides another example of how natural compounds can be used to treat human diseases.
Editor in charge: Yue Ming